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Non-Communicable Diseases
Association of SMuRFS with Cardiovascular Risk Factors, Disease Burden and Pharmacological Management in Middle Eastern Patients
A study published by researchers from Jordan, Saudi Arabia, and Qatar has shed light on how Standard Modifiable Risk Factors (SMuRFs) such as smoking, hypertension, diabetes, and dyslipidemia cluster to accelerate disease progression and increasing the risk of severe outcomes like myocardial infarction and heart failure in Middle Eastern patients. The study comprised of 1,859 patients with a family history…
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Cancers
Cancer Drug Testing could be transformed by this new paper based platform: Spheromatrix
Researchers at New York University Abu Dhabi (NYUAD) have developed Spheromatrix, a simple and low-cost technology that enables tumor models to be grown, frozen, and stored for future use in cancer drug testing. The study on development and validation of this technology was recently published in Nature Microsystems & Nanoengineering. Three-dimensional (3D) in vitro tumor models are increasingly recognized as essential…
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Non-Communicable Diseases
Adult Vaccinations for Patients with Cardiovascular Diseases – Saudi Heart Association Position Statement
The Saudi Heart Association (SHA) convened a multidisciplinary expert panel to review the literature and develop evidence-based recommendations for adult vaccinations for patients with Cardiovascular diseases (CVDs). Cardiovascular diseases remain the leading cause of death globally, and the burden is particularly high in Saudi Arabia, where mortality and risk factors exceed global rates. Individuals with established CVD are highly vulnerable…
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Cancers
The Obesity and Cancer Link – Unraveling molecular interconnections and identifying potential therapeutic targets of significance
The link between Obesity and Cancer has emerged as a significant risk factor for a range of malignancies, including melanoma, endometrial, prostate, pancreatic, esophageal adenocarcinoma, colorectal carcinoma, renal adenocarcinoma, and pre-and post- menopausal breast cancer. A narrative review published by researchers from Qatar, Saudi Arabia, UAE, and India offers a comprehensive examination of the molecular interconnections between obesity and cancer…
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Public Health
Male Infertility in Egypt – Epidemiology and temporal trends
Male infertility is a significant global health issue. However, lack of reliable epidemiological data on male infertility in Egypt and the Middle East and North Africa (MENA) region poses a challenge to understanding region-specific risk factors. A recent retrospective study on male infertility in Egypt sought to bridge this gap. The study reviewed the medical records of 3,037 infertile men…
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Public Health
UAE Indoor Air Pollution – Research Strategy
In the United Arab Emirates (UAE), Indoor Air Pollution has become an exceptionally important health issue. Weather conditions like extreme summer temperatures frequently exceeding 42°C (108°F) force residents to spend prolonged periods indoors in tightly sealed, air-conditioned buildings. This high indoor exposure, combined with significant outdoor fine particulate matter (PM2.5) from windblown desert dust and anthropogenic sources, has raised serious…
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Non-Communicable Diseases
Diabetic Foot Ulcer Infections – Carbapenemase Producing Multidrug Resistant Organisms
Diabetic foot ulcers (DFUs) represent one of the most severe and debilitating complications of diabetes, frequently necessitating non-traumatic lower-limb amputations. The clinical challenge of managing DFUs has been profoundly aggravated by the rising prevalence of multidrug-resistant (MDR) bacteria. Among the most alarming of these MDR pathogens are the carbapenemase and extended-spectrum β-lactamases (ESBLs) producing Gram-negative bacteria, including Escherichia coli and…
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Public Health
Expanded Premarital Screening in UAE – Outcomes of Capacity Building Workshops for Physicians
Premarital screening in UAE is a critical public health strategy for mitigating hereditary disorders in the local United Arab Emirates (UAE) population, where consanguineous marriages account for approximately half of all unions. However, the effective implementation of expanded PMS programs relies heavily on the expertise of healthcare professionals, many of whom lack specific training in genetic counselling. To address this…
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Cancers
Colorectal Cancer in GCC Gulf Countries – Diagnosis and Management: Expert Recommendations
Colorectal Cancer in GCC (Gulf Cooperation Council) countries has incidence rates from 9.9 to 15.9 per 100,000 people. Experts are concerned about a rising trend, especially in individuals less than 50 years old, linked to rapid urbanization, poor diet, low physical activity, and increased hereditary risk due to a high rate of consanguineous marriages. Survival rates in the Gulf are…
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Public Health
Influence of High BMI on Male Infertility – Oxidative Stress Markers and Semen Parameters
This is a study on the influence of High BMI on Male Infertility. Infertility affects a significant number of couples globally, with male factors, primarily poor semen quality, contributing to nearly 40% of cases. While the precise causes of infertility are often unclear, this study from Iran investigated the influence of body mass index (BMI) on semen quality and oxidative…
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