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Non-Communicable Diseases
๐๐ป๐๐ถ-๐ถ๐ป๐ณ๐น๐ฎ๐บ๐บ๐ฎ๐๐ผ๐ฟ๐ ๐ฎ๐ป๐ฑ ๐๐ป๐๐ถ-๐ฎ๐ฟ๐๐ต๐ฟ๐ถ๐๐ถ๐ฐ ๐ฝ๐ผ๐๐ฒ๐ป๐๐ถ๐ฎ๐น ๐ผ๐ณ ๐ซ๐ถ๐บ๐ฒ๐ป๐ถ๐ฎ ๐ฐ๐ฎ๐ณ๐ณ๐ฟ๐ฎ ๐ฒ๐ ๐๐ฟ๐ฎ๐ฐ๐
A recent study published in Scientific Reports highlights the potential the promising anti-inflammatory and anti-arthritic potential of the seeds of Ximenia caffra (X. caffra) as a natural approach to managing Rheumatoid Arthritis (RA). Researchers from Al-Azhar University, Cairo University, Zigazig University, and Sinai University analyzed the extractโs bioactive profile using Liquid Chromatography High Resolution Mass Spectrometry (LC-HRMS), identifying key compounds…
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Public Health
Prevalence of Overweight and Obesity in Adults in Middle East
A landmark study involving over 440,000 adults conducted in UAE has revealed that 63.4% of the total population in UAE was either overweight or obese. This cross-sectional, multi-centre design, population-based study analyzed data of all adults aged >18 years who attended the Dubai Academic Health Corporation (DAHC) between January 2018 and August 2023. Overweight and Obesity (OAO) was defined according…
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Cancers
Breast Cancer in the MENA Region – Somatic Mutation Profiling and Therapeutic Landscape
Breast cancer in the MENA region often presents at a younger age and in more advanced stages. While this suggests a unique biological and genetic profile in this region, the available genomic databases lack adequate data from MENA populations to understand the disease drivers and therapeutic opportunities specific to this demographic. To address this gap, researchers at Hamad Bin Khalifa…
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Non-Communicable Diseases
Association of SMuRFS with Cardiovascular Risk Factors, Disease Burden and Pharmacological Management in Middle Eastern Patients
A study published by researchers from Jordan, Saudi Arabia, and Qatar has shed light on how Standard Modifiable Risk Factors (SMuRFs) such as smoking, hypertension, diabetes, and dyslipidemia cluster to accelerate disease progression and increasing the risk of severe outcomes like myocardial infarction and heart failure in Middle Eastern patients. The study comprised of 1,859 patients with a family history…
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Cancers
Cancer Drug Testing could be transformed by this new paper based platform: Spheromatrix
Researchers at New York University Abu Dhabi (NYUAD) have developedย Spheromatrix, a simple and low-cost technology that enables tumor models to be grown, frozen, and stored for future use in cancer drug testing. The study on development and validation of this technology was recently published in Nature Microsystems & Nanoengineering. Three-dimensional (3D) in vitro tumor models are increasingly recognized as essential…
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Non-Communicable Diseases
Adult Vaccinations for Patients with Cardiovascular Diseases – Saudi Heart Association Position Statement
The Saudi Heart Association (SHA) convened a multidisciplinary expert panel to review the literature and develop evidence-based recommendations for adult vaccinations for patients with Cardiovascular diseases (CVDs). Cardiovascular diseases remain the leading cause of death globally, and the burden is particularly high in Saudi Arabia, where mortality and risk factors exceed global rates. Individuals with established CVD are highly vulnerable…
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Cancers
The Obesity and Cancer Link – Unraveling molecular interconnections and identifying potential therapeutic targets of significance
The link between Obesity and Cancer has emerged as a significant risk factor for a range of malignancies, including melanoma, endometrial, prostate, pancreatic, esophageal adenocarcinoma, colorectal carcinoma, renal adenocarcinoma, and pre-and post- menopausal breast cancer. A narrative review published by researchers from Qatar, Saudi Arabia, UAE, and India offers a comprehensive examination of the molecular interconnections between obesity and cancer…
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Public Health
Male Infertility in Egypt – Epidemiology and temporal trends
Male infertility is a significant global health issue. However, lack of reliable epidemiological data on male infertility in Egypt and the Middle East and North Africa (MENA) region poses a challenge to understanding region-specific risk factors. A recent retrospective study on male infertility in Egypt sought to bridge this gap. The study reviewed the medical records of 3,037 infertile men…
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Public Health
UAE Indoor Air Pollution – Research Strategy
In the United Arab Emirates (UAE), Indoor Air Pollution has become an exceptionally important health issue. Weather conditions like extreme summer temperatures frequently exceeding 42ยฐC (108ยฐF) force residents to spend prolonged periods indoors in tightly sealed, air-conditioned buildings. This high indoor exposure, combined with significant outdoor fine particulate matter (PM2.5) from windblown desert dust and anthropogenic sources, has raised serious…
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Non-Communicable Diseases
Diabetic Foot Ulcer Infections – Carbapenemase Producing Multidrug Resistant Organisms
Diabetic foot ulcers (DFUs) represent one of the most severe and debilitating complications of diabetes, frequently necessitating non-traumatic lower-limb amputations. The clinical challenge of managing DFUs has been profoundly aggravated by the rising prevalence of multidrug-resistant (MDR) bacteria. Among the most alarming of these MDR pathogens are the carbapenemase and extended-spectrum ฮฒ-lactamases (ESBLs) producing Gram-negative bacteria, including Escherichia coli and…
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